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Iron is toxic to the digestive tract, central nervous system and cardiovascular system. Multivitamins for pregnant women contain iron and very often cause deadly poisoning in children.

Children can take tablets containing iron for candy. Among these and prescription drugs containing iron, iron sulfate (20% pure iron), iron gluconate (12% pure iron) and iron fumarate (33% pure iron) are most often found. Many over-the-counter products contain iron. Iron poisoning is the main cause of death from poisoning in children. Taking several iron tablets for adults can harm a child. Children’s vitamins containing iron are safe because of the limited number of tablets in the package. However, a severe overdose of iron can be dangerous and even fatal. Iron is a part of many vitamins for adults and children, so light cases of iron overdose are very frequent. Escalating doses of parenteral iron dextran were safely administered over next several days after pretreatment until a total dose of 2 g was achieved.Medical Term: Iron Toxicity, Iron Overload A pretreatment protocol with methylprednisolone, diphenhydramine, and ephedrine was administered prior to infusion of 1 mg of iron dextran on day 1. Despite this dramatic reaction to parenteral iron, a desensitization protocol was attempted with iron dextran after the patient recovered. After one minute, the patient developed an anaphylactoid response characterized by hypotension, chest pain, and syncope, necessitating admission to the intensive care unit. Parenteral total dose iron therapy was planned, and the patient was given a test dose of 25 mg of iron dextran over five minutes. After several blood transfusions, oral iron-repletion therapy was attempted but was unsuccessful because of gastrointestinal intolerance. The patient underwent multiple endoscopic evaluations, but the source of the bleeding could not be located. Monaghan et al provide a case report of an 83-year-old man with iron-deficiency anemia secondary to chronic gastrointestinal blood loss from an unknown etiology. There are several reports of the safe administration of iron dextran to patients with prior episodes of allergic type reactions.